Angus Chen
STAT
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Past articles by Angus:
Several years later, AstraZeneca says its drug extends life for some early-stage lung cancers
The main issue with an AstraZeneca drug was whether disease-free survival translated into overall survival for some lung cancer patients. Now the company says it does. → Read More
Study of trans men suggests that androgen hormone therapy can lower breast cancer risk
New research suggests that the androgens during hormone replacement therapy may play a crucial role in reshaping transgender men’s breast cancer risk. → Read More
What is basal cell carcinoma, the skin cancer Biden just had
“If you have to get cancer, it’s kind of a good one to have because it’s easy to remove," an oncologist said about President Biden's case. "This is an easily curable cancer that should not impact one’s quality of life, prognosis, or survival.” → Read More
An mRNA vaccine for cancers associated with HPV shows promise in mice
A new study of mRNA vaccines in mice points to a hopeful possibility for people with cancers associated with HPV infections. → Read More
American Cancer Society warns about potential impact of missed screenings during Covid
Without make-up visits, some patients may miss out on routine screenings detecting early-stage cancer or precancerous lesions. → Read More
For many older breast cancer patients, study finds radiation doesn’t affect survival
The vast majority of the trials studying radiation didn’t include breast cancer patients over the age of 65. This study focused purely on them. → Read More
Engineered virus shows promise against aggressive form of breast cancer
"This is something that could be used to improve response to immunotherapy without increasing the severity of autoimmune toxicities that women might experience." → Read More
Is mesothelin a key to tackling solid tumors? Some biotech companies are betting that it is
The abundance of mesothelin on various solid tumor cancers has led some researchers to believe that the protein might be key to getting cell therapies and bispecific antibodies to work. → Read More
In the search for therapies for solid tumors, companies are turning to a novel target: claudin-6
Targeted immunotherapies have been remarkably successful in combating blood cancers, but solid tumors have proved far more challenging. Companies are exploring the use of the protein claudin-6 as a promising target. → Read More
Parker Institute extends ‘crazy idea’ funding to two more cancer centers
Sean Parker's cancer institute expands, offering funding for ideas that may be higher-risk than those in a typical NIH grant. → Read More
Virtual Event: "ASH Recap, Live!" 2022
Join STAT for a discussion of the most prominent work presented at ASH 2022 and a look at what's coming in hematology in the year ahead. → Read More
Study points to new ‘king on the block’ for treatment of chronic lymphocytic leukemia
Next-generation BTK inhibitors like zanubrutinib tend to be more precise and have fewer side effects. → Read More
Novartis develops CAR-T therapy that can be made in a fraction of the standard time
Researchers working with Novartis presented trial data Sunday on a new CAR-T cell made with a rapid manufacturing process that cuts the standard 10 days to less than two days. → Read More
‘We’ve got a new target’: Bispecific antibody for multiple myeloma succeeds in mid-stage trial
Researchers had hoped that a protein called GPRC5D might offer a new way to get the immune system to hunt and destroy multiple myeloma cells. → Read More
Bone marrow transplant patients could be spared from ‘bland’ diet, study finds
Bone marrow transplant patients near-universally dislike the "bland" neutropenic diet that hospitals put them on. A new study finds that the restrictions may not be needed. → Read More
In ‘landmark’ study, cell therapy exceeds expectations in melanoma patients
Experts say a new trial shows TIL can soundly beat out an approved immunotherapy for patients with metastatic melanoma. → Read More
Q&A: Siddhartha Mukherjee on the rapid pace of cancer research and ‘luminous’ life of cells
STAT spoke with Siddhartha Mukherjee about cancer treatment, cell therapy research, and his new book, "The Song of the Cell." → Read More
‘It still prevented cancers’: Experts discuss furor over colonoscopy study and dissect the nuances
A consensus that screening does prevent cancer, but also that colonoscopy programs may not perform as well in the real, messy world. → Read More
In gold-standard trial, colonoscopy fails to reduce rate of cancer deaths
“This study provides clear data that it’s not as simple as saying, ‘Colonoscopy is the most sensitive test, and therefore it is the best.’ It still prevented cancers.” → Read More
CAR-T therapy doesn’t work in all cancer cases. Scientists are starting to figure out why
“As you engineer your CAR-T cells, you can make sure they’re not fighting against each other,” a cancer researcher suggests in light of new findings. → Read More