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Study weighs in on heart safety of TNF inhibitors versus other biologics → Read More
Remission rates not inferior to prednisone -- the 'unthinkable' achieved → Read More
Highest risks for anti-CCP antibodies seen for smokers and those with the HLA-DRB1 shared epitope genes → Read More
Less improvement in joint symptoms with longer duration of use and combo regimens → Read More
Large trials show efficacy for ustekinumab and vedolizumab → Read More
Safety profile favorable in psoriasis, psoriatic arthritis, and ankylosing spondylitis → Read More
IgG2 isotype of anti-TIF1 predicted both cancer and mortality → Read More
Similar to malignancy risk with TNF inhibitors and abatacept → Read More
Initiation of biologic therapy early in the course of psoriatic arthritis doubled the remission rate at week 22 in a randomized trial. In patients who had previously received neither methotrexate nor a biologic agent, the remission rate among those who were given monthly subcutaneous golimumab (Simponi) plus methotrexate was 81% compared with 42% for those given methotrexate alone (P=0.004),… → Read More
Earlier use in rheumatoid arthritis may improve efficacy → Read More
Risk for rheumatoid arthritis declined with many years' cessation, but some risk remained → Read More
Will checkpoint inhibitor-related arthritis outstrip RA in frequency? → Read More
Targeting B cells during prodromal phase of rheumatoid arthritis shows promise → Read More
The strongest risk factor was the presence of tophi → Read More
Newer treatments make inroads, but risks and obstacles remain → Read More
Three questions on fine-tuning treatment for rheumatoid arthritis → Read More
Patients remained off DMARDs for more than a decade → Read More
The more severe and frequent the abuse, the greater the risk of arthritis in adulthood → Read More
High rates of Crohn's disease and ulcerative colitis seen in patients with giant cell arteritis → Read More
* Asymptomatic men and women were at increased risk for clinically diagnosed gout during almost 30 years of follow-up when their baseline serum urate level was elevated, according to a Swedish disease risk factor database. * Realize that asymptomatic hyperuricemia is common, with an estimated prevalence of 10% to 20% in Western populations, but only 10% to 20% of individuals with hyperuricemia… → Read More